Diffusing protein binders to intrinsically disordered proteins
Crossref REST API · 学术索引收录 · 来源发布：Wed Jul 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time) · 本站收录：Thu Oct 08 2026 11:07:46 GMT+0000 (Coordinated Universal Time)
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Abstract Proteins that bind to intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) with high affinity and specificity could be useful for therapeutic and diagnostic applications 1–4 . However, a general methodology for targeting IDPs or IDRs has yet to be developed. Here we show that starting only from the target sequence of the input, and freely sampling both targ
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