Selection and prioritization of candidate combination regimens for the treatment of tuberculosis.
Europe PMC REST API · Indexed academic record · Source published: Wed Feb 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) · Indexed here: Thu Oct 08 2026 09:07:53 GMT+0000 (Coordinated Universal Time)
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Accelerated tuberculosis drug discovery has increased the number of plausible multidrug regimens. Testing every drug combination in vivo is impractical, and varied experimental conditions make it challenging to compare results between experiments. Using published treatment efficacy data from a mouse tuberculosis model treated with candidate combination regimens, we trained and externally validated
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