Predicting the conformational flexibility of antibody and T cell receptor complementarity-determining regions.
Europe PMC REST API · Indexed academic record · Source published: Thu Oct 16 2025 00:00:00 GMT+0000 (Coordinated Universal Time) · Indexed here: Thu Oct 08 2026 09:08:13 GMT+0000 (Coordinated Universal Time)
Saved source excerpt
Many proteins are highly flexible and their ability to adapt their shape can be fundamental to their functional properties. For example, the flexibility of antibody complementarity-determining region (CDR) loops influences binding affinity and specificity, making it a key factor in understanding and designing antigen interactions. With methods such as AlphaFold, it is possible to computationally p
This is a cited excerpt from the source. Read the original link for the complete text. Automated indexing and topic classification do not constitute fact verification.